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Predicting glaucoma risk in patients with high eye pressure

January 2007

US researchers say that they have developed a way to identify high-risk individuals who could most benefit from preventive treatment for glaucoma.

The study used five key factors to detect glaucoma risk: age; pressure inside the eye; cup/disc ratio (a measurement of the optic nerve); thickness of the cornea; and a combination of measurements from computerized visual field tests.

These factors help determine an individual's risk of developing glaucoma over five years, says lead researcher Mae Gordon, a professor in the ophthalmology department at the Washington University School of Medicine in St. Louis, Missouri.

Using these risk factors, the researchers found it was possible to predict which patients would benefit most from pressure-lowering treatment, and which patients would experience little or no benefit.

Glaucoma is one of the most common causes of blindness in the world, and affects 1 in 100 Canadians over age 40.

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